Ninja nerds, join us in this video where we discuss the histology, anatomy, and function of smooth muscle within the human body. The only tissues which perhaps could be confused with smooth. Trichrome stains smooth muscle cytoplasm red and collagen blue or green. It is also concerned there with the formation of plasma lipoprotein as a normal responsibility.
A more chronic measure of the role of cardiac angiogenesis is the massons trichrome stain of the area of cardiac injury. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Click on the button below the histology image and you will hear me give a brief description of the histology slide. Histology is the study of the microscopic anatomy of cells and tissues of plants and animals. The majority of cells in the tunica media are smooth muscle cells. Well take up the quiz below and see just how well you will do.
I have added the missing description and slide below. Much of the connective tissue looks light blue, striations of cardiac muscle cells are visible. Histology muscle 4 the pictures shown here are taken from blue histology. In many, the nucleus will be out of the plane of section. They do not have visible striations as their actin and myosin fibers do not form repeated segments. Smooth muscle can be confused easily with ordinary connective tissue. There are many functions of smooth muscle, from moving food along the digestive tract, to pulling hair erect in response to cold or fear. By examining a thin slice of bone tissue under a microscope, colorized with special staining techniques, you see that these seemingly simple bones are actually a complex microworld. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
They have been reduced in size for easy download, but otherwise unaltered. Instead of having motor units, all cells within a whole smooth muscle mass contract together. Histology, blood vascular system statpearls ncbi bookshelf. Muscle histology of muscle and bone type skeletal cardiac smooth nucleus multinucleated.
Smooth muscle is made up of cells that contain a single central nucleus. It also helps us understand the relationship between structure and function. Vascular smooth muscle cells and the comparative pathology. Muscle histology functions of muscle tissue types of muscle tissue skeletal muscle cardiac muscle smooth muscle types of muscle tissue similarities a free powerpoint ppt presentation displayed as a flash slide show on id. Smooth muscle is specialized for slow and sustained contractions of low force. The books homepage helps you explore earths biggest bookstore without ever leaving the comfort of your couch. Contraction of the arrector pili muscle causes the hair follicle to stand on end, creating goose bumps. Smooth muscle is referred to as an involuntary muscle. This book chapter is open access distributed under the creative commons attribution 4. Muscle tissue is responsible for most types of body movement. You may already have noticed this when looking at epithelium.
Muscle and nervous tissue quiz yakima valley college. Notice the long spindleshape cells with a central nucleus and the lack of striations. Development of skeletal muscle from mesoderm occurs by mononucleated myoblasts fusing together to form mutinucleated myotubes that express contractile proteins forming sarcomeres within myofibers. Massons trichrome stain an overview sciencedirect topics. Smooth muscle cells are spindleshaped and much narrower than skeletal and cardiac muscle cells. Pathology outlines female urethra anatomy and histology. Basic histology smooth muscle, longitudinal section. Smooth muscle is nonstriated and consists of histologically distinct cells. Ranked list of possible diseases from either several symptoms or a. Smooth muscle smooth muscle named as such because the cells do not have striations is present in the walls of organs that contain a lumen like the urinary bladder, uterus, stomach, intestines, and in the walls of large vascular tubes, such as the arteries and veins of the circulatory system. However, smooth muscle has other properties in addition to contractility. We are proud of spreading free medical books for more than medical students and doctors all. What is the source of the spontaneous rhythmicity of g. Smooth muscle does not have the three levels of connective tissue ensheathment typical of many skeletal muscles, due in part to the different role that these muscle fill.
Cardiac muscle cells are bigger than smooth muscle cells and smaller than skeletal muscle cells. It is found in the walls of ducts and blood and lymphatic vessels, as well as in the walls of the digestive, respiratory and urogenital tracts. Striated muscle skeletal musculature, striated in appearance under microscope. Blue histology muscle the only tissues which perhaps could be confused with smooth muscle are dense regular connective tissues and peripheral nerves.
Nucleus, red blood cells and muscle all will stain blue. Contractility is a fundamental property of cells and the majority of them contain essentially the same contractile machinery as that found in muscle cells. Smooth muscle consists of spindle shaped cells of variable size. Oblique arrangement of thick and thin filaments in a smooth muscle flex. In glomangioma, the histopathology shows dilated venous channels that resemble venous malformations figures 1, 2. Combination of glomus cells, smooth muscle cells and vasculature. Veterinary histology martin, meek, and willebtry 4. It is composed of muscle cells, or myocytes, all of which share the fundamental property of contraction. The largest smooth muscle cells occur in the uterus during pregnancy 12x600 m. However, cardiac muscle fibers are shorter than skeletal muscle fibers and usually contain only one nucleus, which is located in the central region of the cell. This diagram shows a few of the cells that can be seen in the stained section below. Smooth muscle is mesoderm in origin and contributes to many different tissues including the muscular wall of the gastrointestinal tract, respiratory tract, artery walls, bladder wall, uterus, seminiferous. Smooth muscle protein translocation and tissue function. Urologic surgical pathology, 3rd edition, 2014 lined by urothelium proximal 23, stratified and pseudostratified columnar and squamous epithelium distal.
Smooth muscle is always seen in sections of organs. This complex image offers very few clues that are intuitive. Structure and function of smooth muscle with special reference to mast cells 353 1 is a 21amino acid peptide with a strong va soconstrictor activity, first isolated from the. Smooth er in liver cells is the site of enzymes detoxifying phenobarbital and other foreign chemical materials. Smooth muscle medical university of south carolina. The chromatin is finely granular and the nucleus contains 25 nucleoli. April 01, 2020 muscle tissue is one of the four main types of tissues that allow the human body to function properly. Study 75 muscle tissue histology flashcards from kelly l. Primary human aortic smooth muscle cells between passages 6 and 10 were used in all experiments.
The glomus cells stain positively for vimentin and. The tunica media is easily appreciated in some vessels as the cytoplasm of the abundant myofiber stains pink, while the nucleus stains blue and normally appears long and stretched to a prolated spheroid. Smooth muscle manages contraction of nonvoluntary muscles. The cells are spindle shaped, and the nucleus is central. As expected, the smooth muscle lacks the arrangement of the actin and myosin, and there is no observable striations. Mesenchymal tumor composed of modified smooth muscle cells arising from the glomus body. Collagen and elastic fibers can be found in close apposition to smooth muscle cells, depending on the function of the tissue and the organ where they are found. Cardiac muscle cell anatomy humor science cells medical science histology slides traditional books autonomic nervous system human anatomy. The larger muscular arteries when cut in cross section appear as swirls of smooth muscle. Predominantly cutaneous, most common in subungual region of the finger but may occur anywhere. The most striking feature of skeletal muscle fibers is the presence of striations, or lines, visible in longitudinal sections of the muscle.
In muscle cells, however, a larger proportion of the cells resources are given over to this function than in other cell types. What is the function of gap junctions in smooth muscle. The role of smooth muscle in human physiology is more expansive than skeletal muscle having a role in nearly every organ system ranging from creating vascular resistance to uterine contractions. There are numerous blood vessels within the myometrium. Apr 22, 2020 histology is the science of the microscopic structure of cells, tissues and organs. This page describes skeletal muscle histology which can identify crossstriational structure and or properties related to contractile speed and fatigue. Smooth muscle containing tissue needs to be stretched often, so elasticity is an important attribute of smooth muscle.
Pdf structure and function of smooth muscle with special. The integumentary system, which is comprised of skin, hair, nails, and various exocrine glands, is the largest organ of the human body human skin is divided into two main parts. Smooth muscle has inherent contractility, and the autonomic nervous system, hormones and local metabolites can influence its contraction. Epithelium is derived from endoderm of the urogenital sinus and the surrounding connective tissue and smooth muscle tissue is derived from splanchnic mesenchyme bostwick. This histology stain is used to stain striated muscle fibers and mitochondria.
Module 2 histology exam study guide by jeepinitreal includes 25 questions covering vocabulary, terms and more. Sep 26, 2016 this feature is not available right now. Smooth muscle also has specific elastin and collagen receptors to. Trichrome stains smooth muscle cytoplasm red and collagen blue or green actin, desmin and calponin stain smooth muscle, but are nonspecific because they also stain myofibroblasts smooth muscle myosin and hcaldesmon are more specific for smooth muscle versus myofibroblasts am j dermatopathol 2006. Cardiac muscle cells produce hormones important for the regulation of fluid balance in the body.
A free powerpoint ppt presentation displayed as a flash slide show on id. In this histology slide of the tongue, ptah stains the collagen pink, fibrin blue, and striated muscle blue as well. Sm contractile function can be regulated via expression and distribution of the. Cardiac muscle fibers also contain many mitochondria. Cardiac muscle is striated and organized into sarcomeres, possessing the same organization of myofilaments as skeletal muscle. Home books junqueiras basic histology, 14e previous. Smooth muscle is found in the walls of the hollow internal organs such as blood vessels, the gastrointestinal tract, bladder, and uterus. Smooth muscle cells have been observed contracting in a spiral corkscrew fashion, and contractile proteins have been observed organizing into zones of actin and myosin along the axis of the cell. Look at this scanning em of smooth muscle from the urinary bladder of a guinea pig.
The contractile proteins in smooth muscle are not regularly repeated and therefore cross striations are not produced. Unlike venous malformations, they demonstrate single to multiple rows of surrounding cuboidal glomus cells figures 3,4. World health organization, central nervous system, reference book, fiction and nonfiction, blue books, colour images, genetics, free ebooks, cancer. Smooth muscle is under control of the autonomic nervous system. Smooth muscle cell reprogramming in aortic aneurysms. These include smooth muscle tissue that generates force relatively slowly with tissue activation but can maintain this force over an extended period of time tonic smooth muscle, and smooth muscle tissue that generates force relatively quickly with tissue activation but does not maintain this force over time phasic smooth muscle. The abundant protein in skeletal muscle can be catabolized as required to support maintenance of other tissues.
Development of smooth muscle, skeletal muscle and cardiac muscle can be found in other notes. Histology of muscle and bone wright state university. Better imaging techniques developed in the last 5 10 years have proven this assertion wrong. A comprehensive database of more than 48 histology quizzes online, test your knowledge with histology quiz questions. Smooth muscle is also present in the eye, where it functions to change the size of the pupil and in the skin where it causes hair to stand erect in response to low temperatures or fear. What are the mechanisms by which contraction in smooth muscle can be regulated 5. The cells stick together and are connected by specialised cell junctions, called gap junctions. Cardiac muscle, the myocardium, consists of crossstriated muscle cells. The dermis is made of connective tissue and is covered on its surface by a thick layer of stratified squamous epithelium that we call the epidermis.
For smc differentiation, hasmc were incubated with medium 231 containing smooth muscle differentiation supplement smds containing 1% fbs and 30. If you use this online study aid, please refer to your textbooks and atlases for. To find the muscle layer, look at the at slide at the lowest power this is about the same as looking at the glass slide with the naked eye. Here youll find current best sellers in books, new releases in books, deals in books, kindle ebooks, audible audiobooks, and so much more. Under the microscope note that fascicles of smooth muscle are arranged in various planes. Smooth muscle sm tissue is a complex organization of multiple cell types and is regulated by numerous signaling molecules neurotransmitters, hormones, cytokines, etc. This book is distributed under the terms of the creative commons attribution. This is a section of smooth muscle from the tunica media of a muscular artery.
Specifically, massons trichrome utilizes three stains to selectively identify muscle, collagen fibers, and fibrin. One of the things that will be expected of you is a good understanding when it comes to histology, and below is what is considered the toughest mcq test on the course. The boundaries of individual fibers are indistinct. Exploring the aesthetics of medical science, johns hopkins school of medicine professors christine iacobuziodonahue and norm. Muscle tissue is one of the four main types of tissues that allow the human body to function properly. Smooth muscle cells may secrete a complex extracellular matrix containing collagen predominantly types i and iii, elastin, glycoproteins, and proteoglycans. Vascular smooth muscle cells and the comparative pathology of atherosclerosis, current basic and pathological approaches to the function of muscle cells and tissues from molecules to humans, haruo sugi, intechopen, doi. Encapsulates blood vessels and lines intestinal tract, uterus, and bladder. This article will describe the histology of smooth muscle, together with its properties. Intercalated discs may be more difficult to find, but nuclei stand out very clearly. Dont expect every fiber in a section to exhibit a nucleus. Muscle tissue junqueiras basic histology, 14e accessmedicine. Some relatively recent books may still have old information.
The arrector pili muscle is a smooth muscle that attaches to the hair follicle, on one side, and the dermis, on the other. Development of skeletal muscle, cardiac muscle and smooth muscle can be found in other notes. Skeletal striated muscle is the most abundant type over 400 distinct muscles, is the only muscle under voluntary control, and in individuals with normal body mass index, represents approximately 40% of their body weight. Smooth muscle cells contain one centrally placed nucleus. The smallest are found around small arterioles 1x10 m. Histology slides, medicine notes, lymph nodes, lymphatic system, school stuff, map, location map, cards, maps. The first of the esophagus features striated, voluntary muscle, while the latter 23 is involuntary smooth muscle. See more ideas about muscle, skeletal muscle and histology slides. Ppt muscle histology powerpoint presentation free to. Histology slides uni life reproductive system biology smooth muscle blue image school online free medical diagnosis assistant. Book october 2017 with 20,798 reads how we measure reads a read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a.
Our online histology trivia quizzes can be adapted to suit your requirements for taking some of the top histology quizzes. Smooth muscle in the large blood vessels produces elastic fibers important for their resilience. Jun, 2014 smooth muscle with histology for medical school. Smooth muscle cannot be controlled consciously and thus acts involuntarily. Microscopic anatomy and organization of skeletal muscle cross section of a skeletal muscle page 239 of lab book blue epimysium green perimysium yellow. A smooth membrane system is found in muscle fibres as the sarcoplasmic reticulum. Smooth muscle consists of spindle shaped cells of variable. Quizlet flashcards, activities and games help you improve your grades. It is capable of synchronous contractions that are based on a similar mechanism to the one in skeletal muscle. To maximize the force that human skeletal muscle can produce, the muscle cells.
1075 844 1398 1391 82 958 1032 501 580 57 616 89 1379 997 958 1369 296 87 146 1150 765 869 988 117 928 614 1408 1303 282 1385 968 604 916 964 1201 420 865 486 872 535 901 294 764 162